Protex Co., Ltd.
Now, additional vaccination for the new Corona Omicron vaccine! Just a little bit before that, an antibody test that can be used as a basis for vaccination. Let’s consider the necessity and inoculation period. For those who have experienced adverse reactions or poor physical condition after vaccination, a means to consider the timing of vaccination
This time, according to a survey at our own laboratory, 40% of people who have antibodies against the conventional strain do not have antibodies against the Omicron strain BA.5 (where infections are spreading). I understand. In addition, we found that there are some people who have antibodies against Omicron strain BA.5, but their antibody levels (antibody titers) are not sufficient.
We believe that the results of this survey will serve as a basis for deciding whether or not to vaccinate against the Omicron strain. [Background of conducting the survey]
While the number of people who have been vaccinated multiple times is increasing, there are some people on SNS who are worried about the lack of convergence of the new coronavirus infection and who have doubts about vaccination. We conducted this survey because we thought it would be very meaningful to consider ways to eliminate that anxiety. In this report, we conducted an antibody test for the Omicron mutant and verified the test results.
By the way, the number of people in Japan who have been vaccinated against the Omicron strain is currently over 32.17 million, or 25.5%. (as of December 12)
Purpose of inspection: Investigation of the amount of antibodies against the new coronavirus.
Inspection method: Quantitation of antibody against spike protein fragment (receptor binding region [*1]) of conventional strain and Omicron strain (BA.5 (BA.4)).
Target: 238 people living in Japan who received Easy Doc (R) “mutant strain antibody test” and consented to the survey
Sample collection period: September 12, 2022 to December 7, 2022. 【Survey results】
As a result of testing the subjects at our in-house laboratory, approximately 90% (219 people) had antibodies against the conventional strain. This result was equivalent to the result of the antibody prevalence epidemiological survey regularly conducted by the Ministry of Health, Labor and Welfare. In addition, about 80% (193 people) of the total have antibodies against the currently prevalent Omicron BA.5 (BA.4) strain.
In addition, when we examined the test results of 193 people who had antibodies against the BA.5 strain in detail, it was found that about 40% had an antibody amount (antibody titer) less than the reference value (120 AU/ml) [*2]. I understand that you are here.
It would be very reassuring if we could examine the amount of antibody (antibody titer) in detail for each type of antibody against the new corona mutant strain and know that we have a sufficient amount of antibody against the infected mutant strain. can have It is important to know your exact situation, not just the amount of antibody (antibody titer). By taking an antibody test against the Omicron variant, for example, it is possible to know the antibody titer against the currently prevalent BA.5. Also, if you are still worried about vaccination against the Omicron strain, it may be one of the criteria for consulting with your doctor.
[About the mutant antibody test used this time]
Until now, antibody tests have shown that antibodies are produced by infection or vaccination, but it is not possible to know which mutant strains have the antibodies.
For this reason, Protex Co., Ltd. (Headquarters: Wako City, Saitama Prefecture, Representative Director: Masao Nishizaki) has developed an easy doctor that can test antibodies against four types of Omicron strains BA5, BA2, BA1, and conventional strains at home. (R) We provide “mutant strain antibody test”.
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▽ Past research (reference)
We examined the amount of antibody (antibody titer) in the following three people who are considering vaccination.
Mr. A (50s): 3rd dose of conventional vaccine (monovalent), 8 months after vaccination. No awareness of infection.
Mr. B (40s): 4th dose of conventional vaccine (monovalent), 6 months after vaccination. No awareness of infection.
Mr. C (40s): Not vaccinated. No awareness of infection.
The antibody possession status corresponding to the Omicron strain resulted in different results. From the above figure, Mr. B, who has the antibody corresponding to the Omicron strain, and Mr. A, who is a recipient of the conventional vaccine (monovalent), has been confirmed. However, in Mr. B, antibodies corresponding to BA5, which is currently prevalent, were not detected. Antibodies to the Omicron strain were detected in Mr. C, who had not been vaccinated, indicating that he was infected. In addition, when Mr. A was additionally investigated after receiving the Omicron strain vaccine (bivalent), it was confirmed that the amount of antibody (antibody titer) against the Omicron strain increased.
[Reason why “mutant antibody test” is required]
There are individual differences in the degree to which antibodies are produced by vaccination or infection. In addition, it is known that the amount of antibody (antibody titer) that rises once after vaccination decreases as the days pass. By doing the Easy Doc (R) “mutant antibody test”, you can know how effective the vaccination is and how much the antibody is several months after the vaccination. [Benefits of taking an inspection]
Knowing that you or your relatives have sufficient antibodies can help you feel more secure in your everyday life. Also, if you know that your antibody level (antibody titer) is low, you can pay more attention when traveling or watching sports. In the future, we would like to develop it into a judgment material for vaccination timing. [Outline of service]
Product name: Easy Doc (R) “mutant strain antibody test” (for research) [Image 7
Inspection items: Omicron strain antibody test (RBD region), antibody test to examine the effect of vaccination.
Antibody test to check past infection history (optional test) Blood collection method: Self-collection * Blood collection can be done at home Inspection method: Microarray automatic measurement system, ELISA method Application method: Apply from the “Easy Doc (R)” site on your smartphone or PC Sales price: 9,900 yen (tax included)
Easydoc (R) URL is https://easydoc.jp/
Company name: Protex Co., Ltd.
Address: Wako Riken Incubation Plaza, 2-3-13 Minami, Wako City, Saitama Prefecture
Business description: Research and development of highly sensitive detection technology for viruses and bacteria, manufacturing and sales of reagents, etc.
*1 An antibody that binds to the receptor binding region can be a neutralizing antibody.
*2 The standard value (120 AU/ml) refers to the amount of antibody (antibody titer) that is estimated to have a sufficient virus-blocking effect in experiments using cultured cells (this estimate is based on experimental results. ). However, it does not mean that the effect will be lost if the value falls below this standard value, and the probability of exhibiting a sufficient effect is said to decrease according to the amount of antibody (antibody titer) (for antibodies against conventional strains, half the standard value). probability of about 80%).
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