Okayama University Is systemic administration of prophylactic antibiotics (antibiotics) necessary after cataract surgery?

National University Corporation Okayama University
[Okayama University] Is systemic administration of prophylactic antibiotics (antibiotics) necessary after cataract surgery?

December 22, 2022
National University Corporation Okayama University
[Image 1

-Points of announcement-
The number of drug-resistant bacteria that are resistant to
antibiotics (antibiotics) is increasing worldwide, and it is predicted that the number of people who die from infection with drug-resistant bacteria will increase.
The World Health Organization (WHO) adopted an action plan on antimicrobial resistance in 2015, and the Japanese government formulated an antimicrobial resistance action plan in 2016, promoting the proper use of antimicrobials (do not use them unnecessarily, and to reduce usage).
During and after cataract surgery, intravenous antibiotics and oral administration have been used to prevent infection.
Regarding cataract surgery performed between April 2016 and October 2022, antibiotic drip and oral administration were discontinued in stages from January 2018, and oral administration was discontinued from November 2021. There was no infection.
From this survey, we show the grounds that postoperative infection will not occur if local infection control measures such as antibiotic eye drops are taken before surgery, and that systemic administration of antibiotics (infusion, oral administration) is unnecessary. I was able to.
National University Corporation Okayama University (Headquarters: Kita-ku, Okayama City, President: Hiroshi Makino) Faculty of Health System Integrated Science (Medicine) Department of Biofunction Regeneration and Reconstructive Medicine (Ophthalmology) Professor Toshihiko Matsuo, Faculty of Medicine and Dentistry In April 2016, Hidehiro Hagitani, associate professor of general internal medicine in the field of pharmacy (medicine), Masahiro Iguchi, pharmacist of Ochiai Hospital pharmacy in Maniwa City, Okayama Prefecture, Noriyasu Morisato, pharmacist, and Tatsuya Murase, Chief Technologist of the laboratory department, etc. ~ We looked back on 2149 cases of cataract surgery performed at Ochiai Hospital by October 2022, divided into five periods.
1. The period when the intravenous drip of antibiotics was performed during the operation and the oral administration was performed for 2 days after the operation
2. Period when oral antibiotics were taken from before surgery to 2 days after surgery
3. Time when other antibiotics were administered from preoperative to postoperative
4. Period when oral antibiotics were taken only once before surgery 5. Time when internal medicine was discontinued
No postoperative infection was observed during all five periods. From this survey, it can be said that systemic administration of antibiotics to prevent infection is not necessary in cataract surgery. The results of this research were published in the “International Journal of Environmental Research and Public Health”, a Swiss journal of environmental science and public health, on November 28, 2022. [Image 2

Status of systemic administration of antibiotics (infusion, oral administration) in the five periods in order from the oldest A word from Professor Toshihiko Matsuo
Dr. Hidehiro Hagitani, a specialist in infectious disease internal medicine, started an infectious disease learning / consultation meeting (O-CAST) for medical workers in Okayama Prefecture, and doctors, nurses, pharmacists, clinical laboratory technicians, etc. at public health centers and hospitals. A variety of medical
professionals and medical students are participating. As I
participated in this meeting and learned, I wondered whether systemic administration of antibiotics for infection prevention, which has been used for many years in eye surgery such as cataract surgery, is really necessary.
Around the year 2000, systemic administration of antibiotics was recommended in a lawsuit against postoperative infection
(endophthalmitis) after cataract surgery. I wish I could be the basis. [Image 3

Professor Toshihiko Matsuo
◆ Paper information
Title of thesis: Are Prophylactic Systemic Antibiotics Required in Patients with Cataract Surgery at Local Anesthesia?
Journal: International Journal of Environmental Research and Public Health Authors: Toshihiko Matsuo, Masahiro Iguchi, Noriyasu Morisato, Tatsuya Murasako, Hideharu Hagiya
DOI: https://doi.org/10.3390/ijerph192315796
URL: https://www.mdpi.com/1660-4601/19/23/15796
◆ Detailed research content
Is systemic administration of prophylactic antibiotics (antibiotics) necessary after cataract surgery?
 https://www.okayama-u.ac.jp/up_load_files/press_r4/press20221221-1.pdf ◆ Reference
・Graduate School of Integrated Sciences in Health Systems, Okayama University  https://www.gisehs.okayama-u.ac.jp/
・Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
・Ophthalmology, Okayama University Hospital
◆ Reference information
・[Okayama University] Kampo medicine brought by Ganjin Wajo is the source of systematized Kampo medicine prescription in modern Japan!  https://prtimes.jp/main/html/rd/p/000000989.000072793.html
・[Okayama University] Introduced refraction test using a spot vision screener in health checkups for 3-year-old children at the Okayama City Health Center ~Improved detection of refractive error that causes amblyopia, enabling early ophthalmology consultation~
・[Okayama University] Application of plant genome analysis method to human disease “squint” for the first time!
・[Okayama University] Discovery of the molecular mechanism of protection of retinal photoreceptors by photoelectric conversion pigment NK-5962!
・[Okayama University] Discovery of neuroprotective effect of photoelectric conversion dye NK-5962!
・[Okayama University] Discovered the protective effect of the functional pigment NK-4 on retinal photoreceptors!
・[Okayama University Health Innovation] Presented the results of international joint research on the elucidation of the
neurotransmission mechanism between photoelectric conversion pigment thin film type artificial retina (Okayama University method artificial retina OUReP (TM)) and retinal cells
・[Okayama University] Watching TV in childhood leads to poor eyesight in school age
・[Okayama University Health Innovation] Follow-up by IgG4 blood test for lacrimal gland IgG4-related disease
[Image 4d72793-1124-32f4944714f8eb55fb5f-5.jpg&s3=72793-1124-37125f189ffbdd72268f2dec1f48f093-982x310.jpg
[Image 5d72793-1124-5302ad366c2affb0a933-4.png&s3=72793-1124-d39ecd4d5c847dfbbdd34ab21301fefa-1545x230.png
[Image 6d72793-1124-637def1e0a4ecc236530-3.jpg&s3=72793-1124-406500432bc0606c7a359b9dfccdd3a7-1920x1080.jpg
Okayama University Shikata Campus, where Okayama University Hospital is located (Kita Ward, Okayama City)
◆ Inquiries regarding this matter
 Okayama University Academic Research Faculty Department of Integrated Health System Science (Medicine) (Ophthalmology, Okayama University Hospital) Professor Toshihiko Matsuo
Okayama University Shikata Campus, 2-5-1 Shikata-cho, Kita-ku, Okayama City, Okayama Prefecture 700-8558
E-mail: matsuot◎cc.okayama-u.ac.jp
     ※Please replace ◎ with @
-Matters related to cooperation with Okayama University Hospital (Pharmaceutical and medical device companies)-
 Okayama University Hospital New Medical Research and Development Center  2-5-1 Shikatacho, Kita Ward, Okayama City, Okayama Prefecture 700-8558 Please inquire about the relevant project from the URL below.  http://shin-iryo.hospital.okayama-u.ac.jp/ph_company/
-Matters related to cooperation with Okayama University Hospital (for medical personnel and researchers)-
 Okayama University Hospital Research Promotion Division
Industry-Academia-Government Collaboration Promotion
 2-5-1 Shikatacho, Kita Ward, Okayama City, Okayama Prefecture 700-8558  TEL: 086-235-7983
E-mail: ouh-csnw◎adm.okayama-u.ac.jp
-Inquiries regarding Okayama University’s industry-academia-government collaboration-
 Okayama University Organization for Research Promotion Headquarters for Industry-Academia-Government Collaboration
 1-1-1 Tsushimanaka, Kita-ku, Okayama City, Okayama Prefecture 700-8530  Okayama University Tsushima Campus Main Building 1F  TEL: 086-251-8463
E-mail: sangaku◎okayama-u.ac.jp
 Okayama University Media “OTD” (app):
 Okayama University Media “OTD” (web):
 Okayama University SDGs website: https://sdgs.okayama-u.ac.jp/  Okayama University SDGs-Thinking about the sustainability of local communities (YouTube): https://youtu.be/Qdqjy4mw4ik
 Okayama University Image Movie (YouTube): https://youtu.be/pKMHm4XJLtw “Okadai TV” (YouTube): https://www.youtube.com/channel/UCi4hPHf_jZ1FXqJfsacUqaw Industry-academia co-creation activity “Okayama University Open Innovation Challenge” Recruiting co-creation activity partners for the term ending December 2022:
 Okayama University “THE Impact Ranking 2021” Comprehensive Ranking Within the top 200 in the world, No. 1 in Japan!!
 Okayama University “University Brand Image Survey 2021-2022” “University Active in SDGs” Ranked 1st in Chugoku/Shikoku!!
 Okayama University Ranked 1st in Chugoku/Shikoku in the 2022 edition of the “University Image Survey from the Perspective of Company Personnel Managers”!!
[Image 7d72793-1124-8f1c521231ed42e5bfab-6.jpg&s3=72793-1124-c53b97d46f2e54ff5424b99e22aeaf70-1752x734.jpg
National University Corporation Okayama University supports the United Nations Sustainable Development Goals (SDGs). In addition, we have received the government’s first “Japan SDGs Award” Special Award

Details about this release:


%d bloggers like this: