Mikiyukai Medical Corporation
First in Japan! (*) “Next generation regenerative medicine” newly introduced in 3 cities! “Repair Cell Clinic Sapporo-in” opens on Friday, December 1st
……
Repair Cell Clinic (Tokyo Clinic/Osaka Clinic, Chairman: Sadanori Sakamoto), a clinic specializing in regenerative medicine by Medical Corporation Mikiyukai, has introduced Japan’s first (*) “new next generation regenerative medicine,” which is located in Tokyo and Osaka.・We are now able to provide stem cell treatment with higher regenerative ability than conventional regenerative medicine (stem cell treatment) in three cities in Sapporo. (*As of December 1, 2023, researched by our hospital based on published materials from each company)
[Image 1
◆URL https://sapporo.fuelcells.org/
New joint regenerative medicine: Toward an era of differentiation induction “Next generation regenerative medicine” that differentiates and induces what is needed where it is needed
First in Japan! The Ministry of Health, Labor and Welfare has approved a new next-generation regenerative medicine, “Treatment of
arthropathy using autologous adipose-derived stem cells and autologous pre-osteoblast differentiation supernatant”. This patented technology has made “regenerative medicine for joints by inducing
differentiation” possible, making it possible to treat stem cells with higher regenerative ability than conventional regenerative medicine (stem cell therapy). As a result, it has become possible to regenerate more articular cartilage, meniscus, and bone necrosis. Regenerative medicine will be further upgraded, avoiding surgery and requiring hospitalization.
This is expected to be highly effective in treating knee
osteoarthritis, hip osteoarthritis, meniscal damage, femoral head necrosis, and osteonecrosis of the knee joint.
What is differentiation induction? Its mechanism and safety (the basis of this patent)
Our bodies contain “stem cells” that can change into various forms, like fertilized eggs.
For example, it can transform into nerves, blood vessels, bones, blood, muscles, etc. This ability to change appearance is called “differentiation.” This process of guiding stem cells, which can be transformed into various forms, to differentiate into specific tissues such as bones and nerves, is called “differentiation induction,” and is the basis of this patent.
[Image 2
What is the next generation of “joint regenerative medicine through differentiation induction”?
This is a revolutionary new era of regenerative medicine in which stem cells can be induced to differentiate into specific tissues. By inducing differentiation, the administered stem cells can be fully utilized and their ability to regenerate into the target tissue can be increased. Furthermore, we do not use any chemical substances or perform any genetic manipulation during this differentiation induction process. Since it utilizes the power of our own cells, there are no safety issues, so you can receive treatment with peace of mind. The wonders of “joint regenerative medicine through differentiation induction” By inducing differentiation in the regeneration of subchondral bone, which is the foundation of cartilage, it has become possible to regenerate more cartilage and maximize the effect on pain. . *What is the mechanism of joint pain?
Do you know how the pain of knee osteoarthritis and osteoarthritis of the hip develops?
Pain occurs only when the cartilage wears away and the bone underneath the cartilage is damaged. The bone beneath this cartilage is called subchondral bone. There are no nerves in the cartilage itself, so you don’t feel pain. However, nerves run through this subchondral bone, so if the cartilage wears away and the subchondral bone underneath is damaged, you will feel pain because of the nerves. In other words, damage to this subchondral bone is deeply involved as a major cause of joint pain.
This subchondral bone has an important role: it serves as the foundation for cartilage formation. In other words, if the subchondral bone is damaged or missing, it will be difficult to regenerate the cartilage as desired, no matter how many stem cells are administered during stem cell therapy.
So, why is cartilage not regenerated unless the underlying subchondral bone is regenerated?
Let’s compare this to the relationship between the soil in a field and the yield of crops grown there.
The larger the area of soil (subchondral bone) in a field, the more crops (cartilage) can be harvested. And crops cannot grow without soil.
The same can be said for the regeneration of joint cartilage. “If the subchondral bone (soil) that is the foundation of cartilage is not regenerated, cartilage will not be regenerated on top of it.” In other words, depending on how much area of subchondral bone is regenerated, This determines the amount of cartilage that will be regenerated.
In conventional stem cell therapy, only a portion of the stem cells administered into the joint are used to regenerate subchondral bone and cartilage.
[Image 3
Therefore, in the next generation of “joint regenerative medicine by inducing differentiation,” stem cells are induced to differentiate so that a large amount of subchondral bone, which is the foundation of cartilage, can be regenerated. By regenerating a large amount of subchondral bone, it has become possible to regenerate more cartilage than with conventional regenerative medicine. In addition, by using inducers to induce pain-causing substances released into the joints, they are able to suppress inflammation 20-30 times more strongly than conventional stem cells.
[Image 4
Comments from Chairman Sadanori Sakamoto
Our hospital opened a new Sapporo clinic on Friday, December 1, 2023. Coinciding with the approval of the next-generation new regenerative medicine “Treatment of arthropathy using autologous adipose-derived stem cells and autologous pre-osteoblast differentiation-inducing supernatant” by the Ministry of Health, Labor and Welfare, there is a sense of mission in the Hokkaido region. We are happy to be able to deliver it to you.
At our hospital, we not only provide treatments that utilize the evidence and experience of treatments such as regenerative medicine, but also provide aftercare such as rehabilitation other than medication, and we offer various services such as partnering with specialized rehabilitation facilities at our own expense. We are ready to respond to your needs.
We have over 8,000 cases of regenerative medicine, and we are a clinic specializing in regenerative medicine that can provide treatment for diseases that are already considered difficult.
If you are suffering from painful symptoms, we also welcome inquiries via email via the web.
“Let’s do things we couldn’t do before!” All for the smiles of our patients. Sapporo-in Overview
◆Clinic name
“Repair Cell Clinic Sapporo-in”
◆Clinical subjects
Regenerative medicine specialty (stem cell treatment, PRP treatment, NK cell immunotherapy)
◆Opening day
Friday, December 1, 2023
◆Location
Xymax Sapporo Odori Building B1F, 5-10 Odori Nishi, Chuo-ku, Sapporo, Hokkaido ◆Access
・1 minute walk from Exit 1 of Odori Station on the subway (Namboku Line, Tozai Line, Toho Line)
・4 minutes walk from Nishi 4-chome Station on the streetcar
・14 minutes walk from JR “Sapporo Station”
[Image 5
◆URL https://sapporo.fuelcells.org/
■“Dr. Sakamoto’s Regenerative Medicine Channel”
https://www.youtube.com/channel/UCJ9fSZkTOxFpVEswk3JvzHw
Corporate overview
Mikiyukai Medical Corporation Regenerative Medicine Specialist Clinic Repair Cell Clinic
Chairman: Sadanori Sakamoto
Address: Tokyo Clinic: New Pier Takeshiba South Tower 3F, 1-16-1 Kaigan, Minato-ku, Tokyo
Osaka-in: Dojima Cross Walk 4F, 1-1-51 Fukushima, Fukushima-ku, Osaka Phone: 0120-706-313
Established: December 2006
URL: https://fuelcells.org/
We accept email consultations and reservations via the web.