Anti-Aging Co., Ltd.
NMN for skin Cosmetic raw material “Penetration type NMN derivative” “Pentide-NMN” Patent application and labeling name acquired as a new substance Also compatible with Inflammageing (inflammatory aging) ……
Anti-Aging Co., Ltd. (Headquarters: Minami-Aoyama, Minato-ku, Tokyo), which first launched human stem cell culture fluid in Japan in 2012 and continues to provide it as a raw material for cosmetics, has developed a new raw material for NMN derivatives specifically for the skin, Pentide-NMN. )’ display name was obtained. A patent application is pending for this raw material as a new substance, and the labeling name has been registered as a new substance, “dihydroniacinamide riboside acetyltri-t-butyltryptophan.”
Anti-Aging Co., Ltd., which first launched human stem cell culture fluid in Japan in 2012 and continues to provide it as a cosmetic raw material, has developed NMN (nicotinamide mononucleotide), which has been attracting attention as a supplement in recent years, and has optimized it as a cosmetic raw material. Pentide-NMN” has been available since February, and the display name has been decided. The display name of “Pentide-NMN” is “dihydroniacinamide riboside acetyltri-t-butyltryptophan,” which is a completely different substance from nicotinamide mononucleotide (NMN), which is already registered as a display name for cosmetics. is registered as. As a result, NMN, which previously could not be incorporated into cosmetics due to patents, can now be used without being bound by patents. “Pentide-NMN” is a product that synthesizes part of the structure of cell-penetrating peptide (CPP) with nicotinamide riboside, which induces NMN within cells, and has the ability to be absorbed transdermally, which conventional NMN does not have. ing. At the same time, its stability in aqueous solutions has been improved, overcoming all of the negative points when incorporating NMN into cosmetics: 1. Patent issues 2. Transdermal absorption 3. Stability.
Motif, a CPP that allows Pentide-NMN to be absorbed through the skin and stabilizes it, is broken down by the action of proteolytic enzymes once it is taken into cells, allowing it to quickly induce NMN. Therefore, it has been confirmed that NAD+ is increased and sirtuin genes are expressed.
In addition, “Pentide-NMN” has been attracting attention in recent years as it suppresses inflammatory cytokines and increases NAD+ not only in aging cells but also in cells in an inflammatory state. It has been suggested that it is also very effective against inflammatory aging.
Effect of sirtuin gene expression
[Image 1: https://prtimes.jp/i/13037/29/resize/d13037-29-39d32523780231d9d06e-0.jpg&s3=13037-29-79454c1f800f8956b910c2b28761b584-872×700.jpg]
[Image 2: https://prtimes.jp/i/13037/29/resize/d13037-29-85c77dc38393321f5b6b-1.jpg&s3=13037-29-2f5d3445dc910464f060820ff5e6a39d-1255×582.jpg] Inflammatory cytokine suppressive effect
[Image 3: https://prtimes.jp/i/13037/29/resize/d13037-29-d035e618c0e82a707849-2.jpg&s3=13037-29-002e2e02b21ed575377363b927a21d20-1034×770.jpg] For inquiries regarding this matter, please contact Anti-Aging Co., Ltd. AOYAMA346, 3-4-6 Minami-Aoyama, Minato-ku, Tokyo 107-0062 Phone: 03-3478-0248e-mail:
info@anti-ageing.co.jphttps://www.anti-ageing.co.jp/
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