National University Corporation Okayama University
[Okayama University] It has been revealed that whether or not ECMO is used has no effect on the survival rate after organ donation, except for the lungs – Providing appropriate information regarding organ donation, which is one of the options for end-of-life care – ……
June 9, 2024 (Reiwa 6) National University Corporation Okayama University https://www.okayama-u.ac.jp/
[Image 1: https://prtimes.jp/i/72793/2256/resize/d72793-2256-ddd9a7c9ee7625fbacbe-0.jpg&s3=72793-2256-938666b8f080f6be38372aefadf4dee2-1946×1110.jpg] -Key points of presentation-
Using the database of the Japan Organ Transplant Network, we investigated the actual state of organ donation after extracorporeal circulation cardiopulmonary resuscitation (ECPR) and the results of transplant recipients (survival rate of transplanted organs) for people who did not receive ECPR. I compared it with
Compared to the non-ECPR group, the ECPR group took a longer time to donate brain-dead organs, and although the survival rate of
transplanted lungs was lower, other organs were comparable.
◆Overview The shortage of organ donors is a serious problem worldwide. Extracorporeal cardiopulmonary resuscitation (ECPR), which attempts resuscitation using extracorporeal membrane oxygenation (ECMO), is an advanced cardiopulmonary resuscitation method for cardiac arrest, but even then, some patients die without recovery of brain function. A certain number exists.
A group led by Lecturer Tetsuya Yumoto and Professor Atsunori Nakao of the Department of Critical Care and Disaster Medicine, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, National University Corporation Okayama University (Headquarters: Kita-ku, Okayama City, President: Yasutomo Nasu) , analyzed the database of the Japan Organ Transplant Network, a public interest incorporated association, and compared a group that underwent ECPR and a group that did not undergo ECPR for donors who had suffered even temporary cardiac arrest. As a result, although the period from presentation of organ donation options to brain-dead organ donation was significantly longer in the ECPR group, the results of transplant recipients (recipients) were similar except for the lungs. I found out something.
The results of transplanted lungs need to be further verified, but if ECPR is performed for cardiac arrest in the emergency room, but brain death occurs, the organ performance will be the same as if brain death occurred without ECPR. It was suggested that provision may also be an option.
The results of this research were published in the British scientific journal “Critical Care” on May 13, 2024, and released by Okayama University on June 3.
◆A word from lecturer Tetsuya Yumoto
We would like to express our respect to the patients and their families who have chosen to donate their organs, as well as to all the medical professionals who have been involved in emergency and transplant medicine, and to Nippon Organ for allowing us to use the extremely valuable data they have accumulated over the years. We would like to express our deepest gratitude to everyone involved, including everyone in the transplant network.
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◆Paper information Paper title: Organ donation after extracorporeal cardiopulmonary resuscitation: a nationwide retrospective cohort study Published in: Critical Care Author: Tetsuya Yumoto, Kohei Tsukahara, Takafumi Obara, Takashi Hongo, Tsuyoshi Nojima, Hiromichi Naito, Atsunori Nakao D O I: 10.1186/s13054-024-04949-5 U R L:
https://ccforum.biomedcentral.com/articles/10.1186/s13054-024-04949-5 ◆About the details of the research: It is clear that whether or not ECMO is used does not affect the survival rate after organ donation, except for the lungs ~ Providing appropriate information regarding organ donation, which is one of the options for end-of-life care ~ https://www.okayama-u.ac.jp/up_load_files/press_r6/press20240603-1.pdf ◆Reference: Okayama University School of Medicine
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◆Contact for inquiries regarding this matter Tetsuya Yumoto Lecturer, Department of Emergency Medicine and Disaster Medicine, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University 2-5-1 Shikata-cho, Kita-ku, Okayama City, Okayama Prefecture 700-8558 Okayama University Shikata Campus TEL: 086 -235-7427 FAX: 086-235-7427 https://okayama-u-qq.sakura.ne.jp/
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